Just my 2 cents.... This varies a great deal from person to person, but I think without any treatment (that helps), it could worst-case lead to permanent and ever-worse nerve damage, not to mention the debilitating pain levels that would be associated with that. If it has a vascular portion, as opposed to strictly neurogenic, then you could also be looking at blood clots. Weakened musculature would likely be another problem.

again, that can vary HUGELY from one person to the next.