Owen, thanks for the update. I just got back from my neuro and he told me to stop the topamax. I was on 25mg at night for the last six days and it didn't do anything for my headaches. Now it's on to 10 mg of amytriptyline and I hope it doesn't turn me in to a zombie, ha. At this point I'm willing to try anything to get rid of this awful headaches. Maybe you need to take the Lyrica a little longer, good luck. Do you have more migraine headaches or are they tension headaches?