Lest, I not have made myself clear in the last post.

Diabetes results in a cascade of dysfunction, high blood pressure>>>kidney damage. High blood pressure>>>blindness. High blood sugar causes vascular malfunction>>poor wound healing>>>amputations. Diabetes, either early onset or type 2, adult onset, usually due to metabolic syndrome is not a good thing.

Diabetes in young females predisposed them to pre-eclampsia and pregnancy failure or complications. Also, high birth weight infants are born to mothers, who altho not diabetic at that time, later develop diabetes. HMM. There is also gestational diabetes.

Thin, healthy people suddenly get type 1, or insulin dependent diabetes out of the blue...yet diabetes does run in families.

Diabetes is one of the biggest causes of functional impairment and life threatening complications. Not to mention, poor sugar control can leave you hyperglycemic or hypoglycemic, both of which can kill you, in pretty quick time frames.

I suspect that perhaps the vascular component of the diabetes could interfere with microvasculature that feeds small fibers.

What I am saying is even people who fastidiously control blood sugar are not usually able to stop progression of small fiber neuropathy. I would sure keep my blood sugar controlled if I had diabetes, with out a doubt, whether or not it is proven at this point or not to help my nervous system. I would assume that poor blood sugar control hurts every organ system, because it damages so many. But a diabetic who controls blood sugar fastidiously, and has progression of SFN can't do much more than that in terms of trying to prevent progression of SNF

Also, of importance is that Glucose Tolerance Testing, should be done on every one with SFN. Many people with SFN will have Glucose Intolerance or abnormal Glucose Tolerance Tests. Often times docs won't want to do GTT because of the new hemoglobin monitoring of blood sugar. I am not sure if the new hemoglobin testing gives the same information that the GTT does.

It is highly complex. I just had a muscle biopsy to see if I have a myopathy, with the thought that some of my symptoms may be myopathic, however, the neuologist, said, it is still likely neurogenic and myopathic changes may be due to neuropathic changes, which could be hereditary. If my muscle biopsy is abnormal which caused which, myopathy causing neuropathy, neuropathy causing myopathy, or some totally different thing causing both.

By the way, diabetes also causes myopathy.

Disease causes and categories are changing, rapidly, and yes, inflammation, autoimmune, and genetic/hereditary triggers are all being researched. In ten years, many diseases will have new names and new causes will be discovered.

But mind your blood sugar!!!