Hello Caya I had a problem taking the Wellbutrin with the Requip and it was brought to my attention by my pharmacist. I took the Wellbutirin for about 3 months and did not feel like it was working, I was on a low dose to begin with and felt more anxious and restless, also couldn't get much sleep. The pharmacist said it was because Wellbutrin and Requip were both stimulants and not good for me because I have a problem with anxiety. I am now taking Effexor and it seems to be working much better. I don't take Azilect so I am not aware of the contraindication with these two drugs.