yes i have been checked for b12 and was still put on it along with a slurr of vitamins for at least 6 months and nothing even at the slightest got better. i have it in my hands and if you apply pressure to any nerve on my body it hurts. i have at times lost 3/4 vision in my left eye that lasted anywher from 20 min. to 1 1/2 hours. i have had memory and speech problems that come and go. walking is hard enough but i get a like drunk walk that comes and goes. shaking, twitching muscle weakness all over, back neck and arm pains. charlie horses all over cramping all over. my fingers lock up when i do small tasks all like i said come and go by themselves or together.