View Single Post
Old 12-21-2007, 03:30 PM
RLSmi's Avatar
RLSmi RLSmi is offline
Member
 
Join Date: Oct 2006
Location: dx'd4/01@63 Louisiana
Posts: 562
15 yr Member
RLSmi RLSmi is offline
Member
RLSmi's Avatar
 
Join Date: Oct 2006
Location: dx'd4/01@63 Louisiana
Posts: 562
15 yr Member
Default I think action of glutamate

as a neurotransmitter in certain areas of the basal gangila, when insufficiently balanced by dopamine, may be one cause of the tremors and/or rigidity. I think that is the logic behind Neulologix's gene treatment of injecting the gene for the enzyme gultamate decarboxylase into this area. The action of this enzyme is to remove one of the carboxylate groups from the excess glutamate to form gamma-amino butyrate, or GABA, which acts as an inhibitory neurotransmitter.
RLSmi is offline   Reply With QuoteReply With Quote