From my reading of the replies and the other information available there seems to be little solid evidence to base a choice between these two. One big difference is the price of Azilect is as much as $8-$9 per day, while Zelapar is available in generic (selegiline) at a small fraction of the cost, a consideration for someone who pays out of pocket. The irony is my Neuro has been reluctant to prescribe ritalin which I have been taking for 8 years, but he does recommend the Zelapar which metabolizes into amphetimines. I am reluctant to switch because I have done pretty well with azilect (cutting my sinemet by 1/3), but I guess its worth a try.
Perry