Our 17 year old daughter has CFS/ME and developed severe Peripheral Neuropathy and was wheelchair bound when her iron stores, Ferritin, became too low. A simple blood test of Iron Saturation and Ferritin will tell you if this is the case. She had a large IV infusion of iron and now takes iron (Nephron) daily and her PN is gone and has not returned for 5 months now. She still fights the CFS but due to meds that she is taking, she is now feeling so much better. We would be happy to share that information if you are interested. Good luck to you.