Serotonin syndrome happens to some people much easier than doctors expect. I experienced it when a supposedly reputable shrink switched me from Paxil to Prozac abruptly without telling me that Paxil is long-acting and Prozac is short-acting. Apparently, there was a period of time the Paxil was still in my system along with the Prozac I had just started, which had the same effect as a double dose, and it seriously messed me up.
I'm no doctor, so you should probably check this out with one, but it is my opinion that using one anti-seizure med (Topamax) to counteract the effects of another (Lyrica) is a bad idea. I've been on Topamax and Lyrica and Neurontin, but only one at a time, never concurrently. Each medication had undesirable side effects, and incidentally, the Topamax did not cause me to lose a single pound.
Hope I'm not hijacking the thread, but I was really alarmed by the list of medications listed by Laurie and felt I should say something. I'm relieved cyclelops jumped on this with some data. I just want everyone to be safe with their meds because sometimes doctors drop the ball.
fanfaire