This is a link to a website that publishes the Medwatch reports on drug
reactions. It demonstrates clearly the neuropathic potential of Levaquin and
also tendon ruptures. (I suspect tendon issues as well, even if they don't reach the rupture stage)
http://patientsville.com/medication/...de_effects.htm
The family of fluoroquinolones has been very rocky medically. Originally, they were supposed to be not FIRST line drugs...but to be used when others fail.
But doctors were encouraged to use them by the drug reps (who represented the drug companies eager for more $$). There have been 4 of them removed from the market by the FDA for serious toxicity issues.
Statistically that is a lot. Only NSAIDs have similar FDA recall situations.
Over the years I've looked for reasons for the toxicity and details always ellude me.
Here is an article from
2001:
Quote:
Ann Pharmacother. 2001 Dec;35(12):1540-7.Click here to read Links
Comment in:
Am J Nurs. 2002 Jun;102(6):13; author reply 13.
Ann Pharmacother. 2001 Dec;35(12):1673-4.
Peripheral neuropathy associated with fluoroquinolones.
Cohen JS.
Departments of Family and Preventive Medicine, and Psychiatry, University of California, San Diego, La Jolla, CA, USA. jacohen@ucsd.edu
OBJECTIVE: To survey cases of fluoroquinolone-associated adverse events that included peripheral nervous system (PNS) symptoms posted on Internet Web sites. METHODS: Cases were obtained with the assistance of members of Web sites formed by people sustaining fluoroquinolone-related events. Information obtained met the standards of MedWatch, and each reported case was assessed using the Naranjo probability scale. RESULTS: In contrast to previous reports suggesting that fluoroquinolone-associated PNS events are mild and short-term, 36 of the 45 cases reported severe events that typically involved multiple organ systems. Although many newer cases are still evolving, symptoms had lasted more than three months in 71% of cases and more than one year in 58%. Onset of adverse events was usually rapid, with 15 (33%) events beginning within 24 hours of initiating treatment, 26 (58%) within 72 hours, and 38 (84%) within one week. Sixty courses of fluoroquinolones were prescribed: levofloxacin (n = 33 cases), ciprofloxacin (n = 11), ofloxacin (n = 6), lomefloxacin (n = 1), trovafloxacin (n = 1); in eight cases the same antibiotic was prescribed twice. CONCLUSIONS: These cases suggest a possible association between fluoroquinolone antibiotics and severe, long-term adverse effects involving the PNS as well as other organ systems. The severity of these cases may reflect a different population than typically reported to drug companies or MedWatch, which often originate from healthcare providers. In contrast, Internet Web sites may provide a forum for patients experiencing adverse effects that have not resolved promptly. Further study is warranted. Meanwhile the occurrence of PNS symptoms during fluoroquinolone therapy should prompt immediate discontinuation of the agent used.
PMID: 11793615 [PubMed - indexed for MEDLINE]
|
PNS= peripheral nervous system
Have you visited here?
http://www.geocities.com/quinolones/
http://www.fqresearch.org/
There have been people who visited here from time to time about this subject.
It seems the medical community is rather deaf to the reactions to these drugs.
If I could find some link as the mechanisms causing these reactions, there might be a way to heal them. But so far I haven't found good info on them.
The only thing I can suggest is Thiamine and B12 to help the nerves restore themselves. And the tendon issue is just as alarming.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
************************************
.
Weezie looking at petunias 8.25.2017
****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.