of the quinolones. It is not a once a day treatment either.

Levaquin and Avelox are once a day tablets. All of the ones recalled were
also once a day. In general with the exception of Zithromax, once a day
antibiotics tend to be more toxic. There was a once a day sulfonamide called Kynex by Lederle that was taken off the market many years ago.

Cipro still does cause the tendon ruptures however. And those typically happen after the drug is stopped, and months pass. Whatever it is doing takes time
to damage and for a while the ruptures were not connected to Cipro. But when a few doctors had that happen to themselves, it was finally admitted to.
It can happen 6mos after the treatment.

I have really tried to find out how this happens, but I have never seen the mechanism printed out anywhere. I suspect the PN damage is similar, not understood yet.
The fluoroquinolones are very active in the nervous system, so they are doing something there. Floxin was causing seizures for some patients. And the elderly are not recommended to use high doses of any quinolone for this reason.