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Old 12-31-2007, 06:42 PM
SarahO SarahO is offline
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Join Date: Dec 2007
Posts: 134
15 yr Member
SarahO SarahO is offline
Member
 
Join Date: Dec 2007
Posts: 134
15 yr Member
Default And why would a furin inhibitor help ALS?

because if it's a calcium cascade causing mitochrondrial shutdown it would stop that hypothetically- and in TBE viruses furin also plays a role!!!

what also plays a role in TBE viruses- PH!!!! Alkalinity can potentially inactivate TBE.

I web the ALS/Lyme page and have for years now. We have had 4 ALSers locally come to our group and 3 have lived, although that sounds different than it is. 2 were diagnsoed Lyme THEN ALS, so the TBE variant likelihood was stronger from the get go than for your average ALSer. The third was diagnsoed Lyme & ALS within one day!!! The 4th had been diagnosed ALS for a while and was very late and he died in his second week of IV Rocephin from c difficile.

The 3 that lived- 2 did LEDUM and longterm IV Rocephin and Babesiosis treatment. Why would longterm Babs treatment matter? Babesiosis causes acidosis. TBE viruses are activated by acidity. Therefore it makes sense as to why so many of the Lyme/ALS survivors had longterm Babs treatment.

What is ledum? Ledum is

a. an herb, ledum palustre, used for treating Lyme (yes!)
b. an herb which inactivates TBE viruses (yes!)

why does this matter?

TBE VIRUSES

what do they have to do with ALS???

besides, you may say, we don't HAVE TBE viruses in the USA.

not true. We DO have TBE family viruses in the usa. 2 of them I know of...

a. Powassan
b. "Deer Tick Virus" (sounds like joke but is actual dumb name)

so what the heck is this chick blathering on about TBE & ALS for, you may ask??

This is why-

: Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(8):1173-9.
Structure of progressive forms of tick-borne encephalitis

Umanekii KG, Dekonenko EP.

On the basis of long-term follow up (from 2 to 22 years) of 175 patients with various syndromes of progressive forms of tick-borne encephalitis (TBE), evaluation criteria of TBE progression are systematized.

Two basic forms of disease progression are identified: amyotrophic and hyperkinetic, each of them breaking down into a series of leading syndromes. Important for characterizing progressive forms of tick-borne encephalitis (PFTBE) are the time when the disease began to progress and the pattern of progression as well as its stage and severity. PFTBE are correlated with the acute period syndromes.

In long-term follow-up, 68% of patients with PFTBE display transformation of clinical forms of the disease, with

the formation of the lateral amyotrophic sclerosis syndrome

in the overwhelming majority of these patients.


PMID: 6414202
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