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Old 01-20-2008, 07:36 AM
glenntaj glenntaj is offline
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Join Date: Aug 2006
Location: Queens, NY
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glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default Well--

--the most typical presentation of most types of neuropathy--small-fiber, large-fiber, or mixed types (sensory and/or motor) is stocking-glove (though it's not the only presentation).

That's because in many of the underlying conditions that cause neuropathy, the nerves "die back"--they are damaged first inthe areas farthest away from the body core, as it is longer/harder to transport oxygen/nutrients to there and waste products from there.

It's also quite possible to have such symptoms from spinal or other central nervous system dysfunctions (i.e., seizure disorders).

Normally, a normal NCV/EMG study series--if done thoroughly, over many body parts--will rule out extensive large fiber dysfunction. But normal QST does not generally rule out small-fiber dysfunction; it depends on which fibers are being preferentially damaged. I had normal QST, but extensive small-fiber damage revealed by skin biopsy (still the gold standard for diagnosis of that kind of damage).

Could you refresh us as to what type of testing you've had to this point?
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Megan (01-20-2008)