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Old 01-21-2008, 07:27 AM
glenntaj glenntaj is offline
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Join Date: Aug 2006
Location: Queens, NY
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glenntaj glenntaj is offline
Magnate
 
Join Date: Aug 2006
Location: Queens, NY
Posts: 2,857
15 yr Member
Default Glad for the refresh--

--because is does give an idea what to go on.

I noticed two areas that you did not mention, that would be very important to have tested:

First, they should be giving you an immunofixation electrophoresis of serum and urine for rogue monoclonal antibodies (M-proteins). When these are found, the condition is termed monoclonal gammopathy. In about one-third of cases, this is associated with some form of blood dyscrasis, but in two thirds it isn't and is termed monoclonal gammopathy of undetermined significance (MGUS). This is a fairly common cause of neuropathy, as the rogue proteins cross-react with certain components of peripheral nerve.

In keeping in that vein, you should probably be titred up for some of the SPECIFIC antibodies for peripheral nerve--the GM, GD, GQ series, anti-sulfatide antibodies, anti-MAG (myelin associated glycoprotein antibodies), and a few others:

http://www.neuro.wustl.edu/NEUROMUSC...y/mprotein.htm

http://www.neuro.wustl.edu/NEUROMUSC...oantibody.html

(Forgive me if you've had any of these before and this repetitive.)

Last edited by glenntaj; 01-21-2008 at 06:51 PM.
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"Thanks for this!" says:
Megan (01-21-2008), mrsD (01-21-2008)