I am doing ok today. Experienced alot of muscle spasms in legs yesterday. I guess I overdid it on Saturday. I was diagnosed last April(2007). I am 51. I experienced my first flare in March- ssemed to last several months. I suppose I had some minor symptoms prior to that time.

I first tried betaseron (had an allergic reaction after 2 weeks when increasing dose) and then was on copaxone for about 4 1/2 months (had 5 not so much fun IPIR's). So My neuro too me off it it and I had my first tysabri treatment in Dec. During my 2nd treatment, I experienced an allergic reaction and had to have benadryl put in iv. So for my next appointment I have to premedicate with benadryl.

I feel as if I have had more energy since starting tysabri and I am hopeful that it will help me and I can continue to take it. Otherwise I am out of options for now as far as DMd's go.

My biggest fear in terms of dealing with all of this is the unknown. I am trying to take it day by day but that it difficult for a planner.