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Old 01-24-2008, 08:25 AM
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Ronhutton Ronhutton is offline
In Remembrance
 
Join Date: Aug 2006
Location: Village of Selling, in County of Kent, UK.
Posts: 693
15 yr Member
Ronhutton Ronhutton is offline
In Remembrance
Ronhutton's Avatar
 
Join Date: Aug 2006
Location: Village of Selling, in County of Kent, UK.
Posts: 693
15 yr Member
Default Nac

Hi IMark,
The fact that theses researchers had to convert NAC into the amide, to get it past the BBB suggests that NAC can't pass the BBB.
Indeed a search confirmed that.
See
http://www.fasebj.org/cgi/content/full/15/1/243
where it says,
"N-acetylcysteine does not cross the blood–brain barrier"

I have little medical knowledge, I am a chemist, and had better leave the interpretation of the paper you quote, to somone better medically quailified.

Sorry my forulae came out jumbled in my other message,
Best wishes
Ron
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"Thanks for this!" says:
imark3000 (01-24-2008)