Quote:
Originally Posted by Ronhutton
Hi IMark,
The fact that theses researchers had to convert NAC into the amide, to get it past the BBB suggests that NAC can't pass the BBB.
Indeed a search confirmed that.
See
http://www.fasebj.org/cgi/content/full/15/1/243
where it says,
"N-acetylcysteine does not cross the blood–brain barrier"
I have little medical knowledge, I am a chemist, and had better leave the interpretation of the paper you quote, to somone better medically quailified.
Sorry my forulae came out jumbled in my other message,
Best wishes
Ron |
Hello Ron,
I have been taking NAC for some time hoping some of it at least may cross the BBB but now I have second thoughts.
By the way the paper posted by Zflower above states :"Systemic administration of NAC can deliver cysteine to the brain and raise GSH levels in the CNS (Pocernich et al., 2000). "??
Perhapse you have further comment.
Thank you so much for you offering your knowledge generously to the forum