Diagnosed PPMS in May 2003.

Have tried Ribif , intrathecal methotrexate, Tysabri, and plasmapheresis, all to no avail. My disease continues to progress, my right arm and leg are useless, and my left arm and leg are going in that direction as well. This is one hell of a disease...

My doctor is now suggesting intrathecal (spinal) injections of steroids, or possibly Rituxan. At this point, I'd inject gasoline if I thought it would help...