I have been taking Rebif for over 5 years. I need to take Tylenol or whatever when I inject or I still will run a fever. I inject in the evening. In the morning, I need to take more because I still have a low temp. I inject MWF and Saturday mornings are the worst days for me.

I am building my case to get off of this drug. (Whining...I want off.....)

So....for you, will it hurt if you stop for awhile, a few days say and see how you feel? IMHO, I don't think it would hurt at all. It will just give you more info to tell the Dr.