Therese, I, too must apologize for waiting so long to share how I use sinemet CR (actually generic carbi/levo CR 50/200). Each morning, immediately after rising, I take one-half of a regular generic carbi/levo 25/100, along with the CR. Usually, I lose the "shuffles" after about 30-40 min. I repeat that dose in the middle of the afternoon, with good symptom control. The half a regular gives me a little "bump" to take me until the CR does its thing. My neuro is happy with that approach.

If Doreen is having no trouble sleeping, she might be better off not taking another CR at bedtime. Some people, like Steve, take CR before bed with good results, but it is probably best to take the least amount that effectively controls symptoms.

Robert