You'll need to get deep into the mattress to completely get rid of the smell. I was thinking a mix of baking soda or Oxy Clean and hot water poured on the bed and left to air dry. If you like a fresh scent add a some liquid air freshener like Febreeze if you must. If it didn't go all the way through to the other side you don't have to flip. But if it did, well you get the idea. To be completely honest, Febreeze made the smell worse for us but all we had was the first one put out there. Maybe the super odor remover will be best.