and feel that the dosage versus individual physiology is more complex.

I know our brains are all roughly the same but surely our body mass differs widely and this must affect drug absorption. I am 6ft 1 inches tall, weigh 215 pounds, (all muscle of course !! ), surely my reaction to 1mg of Mirapex is different to that of a 5 foot, 120 pound female.

I mentioned this to my Neuro some time ago and he said he hadn't really considered it.

Am I right or wrong in this belief that "body mass" affects PD drug absorption and distribution ?

Neil.