I"ve been using topomax for about a year now @ 75mg. 2 a day for leg pain I think I need a bump now but don't know. was using neutrutuion for 6yrs before that. worked for pain but the side effects got to me. ( check out the web sites) lycica didn't do much for me either. I have to use vicodine also. plus mj, :}..... the topo will make you not want to eat. some peolple I know have the same problem with that also, I drink boost proteint drink to keep my minerals up. and sodas taste like crap too. like most other crabanated drinks with topomax. some hair lose is possible but not always. this is just things I see happened to me. good luck.