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Old 02-09-2008, 10:44 PM
antonina antonina is offline
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Join Date: Nov 2007
Location: manhattan, nyc
Posts: 272
15 yr Member
antonina antonina is offline
Member
 
Join Date: Nov 2007
Location: manhattan, nyc
Posts: 272
15 yr Member
Default Susan, I know exactly how you feel.

I need to literally talk myself into going out to the grocery store (2 blocks away). I'll use every excuse I can to avoid it. But once I'm out, I always marvel at how I could stay indoors rather than go out in the world and see life around me.

I subscribe to a Johns Hopkins newletter and was reminded of an article they emailed a few days ago. Maybe it can help you. Here it is:

Light Therapy and Wellbutrin XL for SAD
January 30, 2008
By Johns Hopkins Health Alerts, www.johnshopkinshealthalerts.com

Now patients with seasonal affective disorder have two effective therapies to relieve depression in the winter months – light therapy and the antidepressant, Wellbutrin XL.

At this time of year, changes in the amount of daily sunlight cause changes in the body’s internal biological clock, known as circadian rhythm. This rhythm is a 24-hour cycle that affects our eating and sleeping patterns, brain wave activity, hormone production, and other biological activities. In some people, less daily sunlight and changes in circadian rhythm can bring about depression. One theory is that the relative lack of sunlight during these times may alter brain levels of certain mood-related chemicals.

If you have SAD, what can you do?

* Light Therapy

Some people with seasonal affective disorder can be successfully treated with exposure to bright light. In one study, 57% of 191 people with SAD responded to light therapy. In another study, light therapy was comparable in effectiveness to antidepressant therapy but worked faster and caused fewer side effects.

Light therapy involves sitting in front of a bank of full-spectrum fluorescent lights for 30–60 minutes each day. Improvement can often be seen within a few days, with symptoms disappearing after two to three weeks. Continued light therapy is needed to prevent a relapse.

* Wellbutrin XL

In 2006 the FDA approved bupropion HCL extended-release tablets (Wellbutrin XL) for the prevention of major depressive episodes in people with a history of SAD. Wellbutrin XL is the first drug officially approved for SAD.

The efficacy of Wellbutrin XL for the prevention of SAD episodes was demonstrated in three double-blind, placebo-controlled trials -- the gold standard of medical research -- in adults with a history of recurrent major depressive disorder in autumn and winter. Treatment was started before the onset of symptoms in the autumn (September to November) and was discontinued following a two-week taper starting the first week of spring (fourth week of March).

In these trials, the percentage of patients who were depression free at the end of treatment was significantly higher for those on Wellbutrin XL than for those on placebo. Combining data from all three studies, the overall rate of people depression free at the end of treatment was 84% for those on Wellbutrin XL, compared with 72% for those on placebo.

These findings have not surprised psychiatrists and primary care physicians, who have long been using antidepressant drugs off label for treating SAD. But the approval of Wellbutrin XL by the FDA adds credibility to the treatment approach.

Clearly I don't know if you have SAD and the article may not resonate with you. Also, Atlanta may have much more sunlight than NYC so SAD may not be an issue.

I'm going to see a psychiatrist in a few weeks and will ask about Wellbutrin. I don't think it can make me more depressed than I am now...lots of weeping episodes over not very serious stuff. Mostly caused by my crappy physical state and wishing I could step outside without a walker. I send you lots of hugs & good wishes.
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