Very interesting. There are many things in common with these two. Both involve an inflammatory response, hypoxia and histamine has a part to play. I suspect the common cause is inflammation not necessarily that they are connected. However I don't know much about IRI so it's just a guess.
I note the research on vitamin C for preventing CRPS post wrist fractures. Further research has been done on this. Professor Scott Reuben now includes vitamin C in the protocols for preventing CRPS post tissue trauma and orthopedic surgery. I also use it post dental work.

Vitamin C is the antioxidant which demolishes inflammation causiong free radicals. Certain things/situations cause the body to make more of these inflammation causing free radicals. Trauma is one stress another. Infact I suspect that people who have a lot of artery blockage may in part blame these free radicals. Stress has a big part to play I believe.

Remember that vitamin C becomes itself a free radical when it demolishes inflammatory causing free radicals. The sensible thing is to have a range of antioxidants to maintain a balance. Personally I believe the safest way to get these is from a diet rich in antioxidants.

However if you have chronic pain it is now known that the brain changes with this kind of pain. The answer for us now lies with retraining the brain to stop the messages from the brain saying that it hurts. Mirror therapy is one way of doing this. It's now used with stroke patients to retrain brain and improve function.

I think the more people who are prepared to think outside the box as you have Vic, the better the outcome for us all.

jeisea

http://www.crps-rsd-a-better-life.blogspot.com