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In Remembrance
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Join Date: Nov 2006
Location: SE Kansas.
Posts: 374
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In Remembrance
Join Date: Nov 2006
Location: SE Kansas.
Posts: 374
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These were published just a year (and two) before Rene LeRiche refuted Weir Mitchell's hypothesis that causalgia was caused by massive nerve damage from high-velocity impacts (mainly guns), and hypothesized that the disease is similar to "....a rare sympathetic disorder"
. He later amplified on this view by asserting that damage to sympathetic nerves caused them to abnormally constrict arteries (SNS vasoconstriction),blocking arterial blood from reaching the capillaries (and thus the cells).
I never bothered to actually try to learn what docs knew back then, as LeRiche abandoned this hypothesis after arterial blood-flow studies showed that it is not affected in RSD. The founder of the SNS view later rejected his own hypothesis, but most RSD "experts" still clung to it until recently; after CRPS replaced RSD; to reflect complete rejection of the SNS view.
I have talked about this research before, but as long as RSD "experts" talk about the SNS, people are going to believe that it is somehow relevant. I'm still looking for an explanation of SNS involvement that doesn't involve vasoconstriction, but haven't found one yet.
I haven't found any explanation of how the SNS can be involved in CRPS-I, which, of course, has no nerve damage whatsoever.
If anyone finds any research showing how sympathetic nerve damage can cause RSD, I hope you post it here. I don't ever expect to see anyone explain how sympathetic nerve damage can cause CRPS-I...Vic
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