...but I'm sure rosebud will stop by soon. In the meantime, if what I suspect is going on is right, then a lot of PWP have a ldopa-induced sensitivity to small increases in their blood sugar that would be dismissed in a normal person. I have to limit my experiments to weekends and other days when I can make mistakes, but my first serious look last weekend was surprising.

The scenario is that when you take a sinemet, over the next two to three hours one's bloodsugar rises slowly at first then quickly to a spike and drops abruptly back to normal. If you eat something with a high glycemic index, the spike is higher and the effect greater. But the values stay within ranges considered normal. I think it is the pattern more than the value but I really don't know.

I do know that during my test last week, i went from a level of 92 (US) to 128 over about 2 1/2 hours and then suddenly dropped back to 94. My PD symptoms went into overdrive and brain fog rolled in.

Today I ate very little. A little roast beef for breakfast. Meds did well all morning. Weakened and had a chocolate milk for early lunch. Symptoms flared and an hour later had a hard time standing. An hour and half after that back to norm. It is now 6:30 PM and still haven't eaten and am doing well.

Now simply not eating is something that can do us a lot of good but only if done correctly. So, once we figure out what's going on, we'll have to figure out what to do about it.

One thing I wonder is what if something other than sinemet triggers it? If so, is it a factor in other neuro problems besides PD and diabetes? I had floated the idea of work groups drawn from across the forums and DocJohn liked the idea. Maybe this is a good subject to test that.