I'm not on Rebif - I take Beta but I inject into the saddle bag area and have never had a problem with it. I don't understand why ANY area isn't OK as long as the medication gets into your system. Like you, I was running out of areas to inject in. I asked the Beta nurse and she said the same thing Punk said - as long as you can pinch and inch you're fine. Works out great for me - I can pinch an inch almost anywhere except the top of my foot!