I've had MS since 1991, at least, and haven't used any DMD's or steroids. That wasn't because of good (or bad) planning though, it was just the recommendation of my neuro(s) based on being mostly spinal lesion afflicted, AND because drugs and I don't get along at all.

I have been on LDN since early 2005, and it has helped. I am still RRMS, and relapsing occasionally, but my EDSS reduced after starting on that drug, and has remained constant since then.

There are good times and bad.

Cherie