Hi Vic..
Thank you for responding
For the most part I do not agree with everything in the articals I post..
But the IRI effects and the fact that inflamation is involved with the starting of RSD to me becomes more obvious the more I read, and I read alot.
Quote:
|
Interesting stuff, and one surprise that tells me that you really do need to try every possible option when using keyword searches in Medscape and PubMed: I never saw the 2nd article in your most recent post. I haven’t done any really intensive research into the literature in the last five years, but at least once a month I scan those resources using keywords like cyanosis; inflammation; central sensitization and IRI in combination with CRPS, and Berthelot’s article never came up. Thanks for bringing it to my attention.
|
As I read articals I watch for terms and wording to use in my searches for more info on what is striking my interest at the time.. I find myself lost in articals going deeper and deeper and it distracts me from pain the deeper I go.. yes I find some interesting stuff and alot of time I do not add CRPS or RSD to my search term but find it because of the direction of the search.
I have also set google to alert me of any new articals that include certain search words.
I totaly understand about the GSE too, and have done my best to make sure new members know of it's benifits.. hmm seems like such an insignificant term "benifits" when we now know antioxadents can infact stop RSD from happening when taken early enouph and can stop spread from happening..
Alot of people I think just can't seem to grasp the idea of antioxadents because it seems so insignificant and too simple a remedy to help enouph to actualy make a diffrence, but in reality if inflammation is the root of RSD then antioxadents are treatment needed and perhaps the lack of antioxadents is actualy a large contributer to the developement of RSD in the first place.
Quote:
About the question in your latest post: So whets with some of us with RSD getting it systemically (full body, organ etc) and some to just one limb.
Maybe it is just that our other systemic symptoms are called other things like carpal tunnel and cardiac syndrome X.
|
BINGO! My thoughts have been thus for along time and that question was looking for your answer.. it seemed so obvious to me so I started my searches without RSd and CRPS in them. Searching terms like "microvascular inflamation" etc.. being that I have symptoms full body I just compared "my" symptoms with what I was reading about and hello they are talking about my symptoms.. not very scientific but ok for a start.. helps being the one with the symptoms less confusion this way.
Quote:
|
It was interesting to read support for Goris’ view that this is a regional inflammatory response, but my problem with all three articles in your previous thread, is that they are still hung up on finding a firm neurological link to RSD; no one has found such a link in the 145 years since this disease was discovered, but they keep trying. I keep trying to persuade people to learn about IRI, because it explains every sign and symptom of our disease in both stages.
|
I am not quite ready to concede to the lack of nerve involvement yeat my friend, and that may be that I just do not have enouph information, but how do you explain the fact that the small nerve fibers are 50% less in people with RSD? and and the sensations like water dripping down my calf when anything bruskes against my leg? ishemia and cyanosis alone would not I think cause some of the symptoms we have like referred pain, electrical jabs etc however I tend to think that the inflammation causes small fiber nerve dammage, how can it not damage the nerves?
Ok lets ignore whether we feel the symptoms are nerve related and look at the whole IRI picture and what it has done to say a leg early in stage 1 or 2.. how can all that damage being done not effect our nerves and our nervous system? and what about dystonia?
I need to study this alot more before I can explain my thoughts well, but right now lets say I am starting to understand that the sympathetic system is not the culprit here, I think the reason sympathetic blocks work so well for some is that it works like a reperfusion to the ichemic condition while at the same time numbing the pain of the reperfusion action (mabie
)
My first block brought momentarily an extreme pain for a minit when I lowered my legs the first time after the procedure then gone in the hot numb swollen feeling from the block. For a minit I thought they made it way worse then it fadded into a buzz of warmth.
Quote:
|
Goris used it in trials with patients still in the first (inflammatory) stage, and his results persuaded the Dutch Government to mandate that physicians make DMSO available to all RSD patients.
|
No suprise there ALOT of treatments are so much more effective for RSD at such an early stage because at that earliest stages RSD is treatable, later antioxadents as some other treatments just staves off progression if you are lucky, and some treatments (ketamine) can put the condition to sleep for a few years or untill reinjuring it.
My recent searches are into the latteral medullary and microinflammation and norepinephrin.. interestin stuff.
However I find I have neglected the work I need to be doing right now and that I am afraid is WCB.. chronic pain and LOE's, I have till the end of this month to get a report into WCAT telling them why I feel their loss of earnings (LOE) is so patently unreasonable that it is not capible of being supported by the Canadian workers compensation act.. there are over 300 apeals here in BC that are waiting this decision by our WCB. this one is very important.
Hugs bud I hope you are well today and as always I look forward to your responses.
Sandra