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In Remembrance
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Join Date: Aug 2006
Posts: 3,772
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In Remembrance
Join Date: Aug 2006
Posts: 3,772
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long term
One thing about the DM is that it has been around for a long time, has been used extensively by all ages, has been abused at huge doses, etc. It has had every opportunity to reveal any problems and yet they are almost nonexistent. In fact, if one compares it to other PD drugs it wins hands down in this department.
The only negatives I have been able to find are the theoretical problems with requip in the liver and the slow metabolism issue for 20% of the population. The first may not be a problem and the second may just require a dosage correction.
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Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
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