Hi Beth.. On LDN 5 yrs in Apr.. No MS Progression since starting. More strength, better balance and NO MS fatigue. I am SPMS.

I started on 3mg and upped it to 4.5mg and have been on that for the last 3+ yrs. I had no adverse side effects, although some ppl complained of insomnia, for the first two weeks, and leg stiffness....(I had a little of that but it went away).

The 2 top reasons I still use it: No Progression and I just plain feel better!!