Funny you should ask about migraines.
It used to be that when I started a flare, I would have 20-30 days of non-stop migraines which would send me running for solumedrol.
I started my first flare since starting (then stoppping, then restarting...but that's for a different thread) Topamax. I'm only taking 50mg in the AM and 50 mg in the PM.
I had one migraine about 1.5 months ago that ended in the Urgent care with shots of demerol, toredol and phenergan. When I woke up the next day it was gone (not how my head aches usually work).
The last week and a half, I've been getting migraines, but not every day, and the've been managable (also not how my headaches usually work) with not much vomiting.
So, in general, I'd say that the Topamax is making a positive difference in regards to my headaches during flares. But I'm interested in increasing the dosage in hopes that it will do even better next time?