Thanks for all the ideas and questions. I'll try to reply more specifically.

I got leg cramps for the first time last summer, when I was on Forteo, which elevated my serum Calcium. When I stopped the drug, the cramps stopped.

They returned about two months ago with a vengeance, and I posted and began taking Mg, with modest results.

Lab tests done at some point were normal, but I'm not sure they've all been checked recently.

I've been hypothyroid for a few months now. Two weeks ago I pulled an article that said that lipoic acid lowers thyroid levels. My endocrine lowered my Synthroid and increased my cytomel and I stopped the lipoic acid.

I do think I get dehydrated; that is true. I don't drink enough.

My iron hasn't been checked in a while.

Also, I am on a LOT of antibiotics. Orally, I am on Biaxin, Ceftin, Diflucan, and Septra. That's been about 2 weeks. (In addition there are two antibiotics that I irrigate with--premade and sterile, Mrs D)

The cramps came back about 3 or 4 days ago. They are really bad, because when I stretch one out, the secodn movement cramps. In fact, any movement will cramp any part of my legs. During the day my hands cramp when I'm holding a book, and this week I noticed I was getting a cramp in a back muscle while sitting--it was mild and worked itself out quickly.

I'll check with my neuro about Baclofen. I take Klonopin at night, and it's done nothing for this. I'm reluctant to take Quinine, but will ask neuro; and I guess I should add the Magnesium back, but it wasn't all that helpful the first time through. I have no idea why they went away last month.

More ideas?