I'd start slowly with the r-lipoic...

I had used alpha lipoic in the past with no effect whatsoever.. NOW brand which is very good. So I think the quality was good. I took 600mg daily for about 2 months, and gave up. It was expensive and I expected "something".

So when I started r-lipoic a few weeks ago, I started at 100mg twice a day,
and that was a huge mistake. Boy did get hyped up and insomniac!

So I cut them in half (I bought tablet form), and only took 50mg in the morning.
After about 2 weeks, I noticed no hyper side effects and increased to 100mg
first thing in the morning. I really like the energy it is giving me, and food cravings (carbs) have plummeted for me.

So I would start slowly.

I have different feelings in my feet too. I think the numbness is getting better.
Some mild aching has developed, which I think is nerves waking up. I've had to put some patches on at night a few times. (I use Salonpas for aching, and Lidoderm rarely for burning).

I am also doing Benfotiamine--and find I have much less water retention than I did. I am not getting response from Lasix anymore! I did not expect that.
So I think this is the benfotiamine doing that, but it may be helped by the
r-lipoic. I've noticed less reactive hypoglycemia as well. So I think the r-lipoic is working like the old metformin did for me in the past --for improving
insulin resistance.

Post here, your results...I think you may be pleased as well.