Jules,

I was diagnosed with no lesions. If it hadn't been for the LP, I'm not sure any one would have thought of MS. Because I had positive LP, ON, and within a few days of steriods, my foot started buzzing (two "whatevers" separated by time and space) I got the "official" diagnosis.

It was about two years after diagnosis before anyone (doctor at UCSF) said they "thought" there *might* be 1 small lesion...(or possibly an artifact).

I haven't had an MRI since, so I don't know if anything else has shown up. But I am proof positive...you CAN have MS with negative MRIs.