Thread: Diet and the "E" word
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Old 03-25-2008, 10:29 PM
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In Remembrance
  
Join Date: Sep 2006
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15 yr Member
lou_lou lou_lou is offline
In Remembrance
lou_lou's Avatar
 
Join Date: Sep 2006
Location: about 45 minutes to anywhere!
Posts: 3,086
15 yr Member
Arrow rosebud is correct -that has been my primary research
I will quote from a medical text

Hypoglycemic brain damage

Roland N. Auer,
Departments of Pathology and Clinical Neuroscience, Faculty of Medicine, University of Calgary, 3330 Hospital Drive N.W., Calgary, Alta., Canada T2N 4N1

Available online 10 November 2004.



Abstract
Hypoglycemia was long considered to kill neurons by depriving them of glucose. We now know that hypoglycemia kills neurons actively from without, rather than by starvation from within. Hypoglycemia only causes neuronal death when the EEG becomes flat. This usually occurs after glucose levels have fallen below 1 mM (18 mg/dl) for some period, depending on body glycogen reserves. At the time that abrupt brain energy failure occurs, the excitatory amino acid aspartate is massively released into the limited brain extracellular space and floods the excitatory amino acid receptors located on neuronal dendrites. Calcium fluxes occur and membrane breaks in the cell lead rapidly to neuronal necrosis. Significant neuronal necrosis occurs after 30 min of electrocerebral silence. Other neurochemical changes include energy depletion to roughly 25% of control, phospholipase and other enzyme activation, tissue alkalosis and a tendency for all cellular redox systems to shift towards oxidation. The neurochemistry of hypoglycemia thus differs markedly from ischemia. Hypoglycemia often differs from ischemia in its neuropathologic distribution, a phenomenon applicable in forensic practice. The border-zone distribution of global ischemia is not seen, necrosis of the dentate gyrus of the hippocampus can occur and a predilection for the superficial layers of the cortex is sometimes seen. Cerebellum and brainstem are universally spared in hypoglycemic brain damage. Hypoglycemia constitutes a unique metabolic brain insult.

Keywords: Hypoglycemia; Metabolism; Brain; Necrosis; Excitatory amino acids; Running title; Brain in hypoglycemia



Forensic Science International
Volume 146, Issues 2-3, 16 December 2004, Pages 105-110
Forensic Neuropathology

http://tinyurl.com/2yl2en



there are many roads that may lead to brain damage/
yet these are well known
too high amounts of sugar - diabetic
very low blood sugar - hypoglycemia

here is a link that is for YOUNG ONSET PD
http://www.emedicine.com/neuro/topic635.htm
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with much love,
lou_lou


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Resolve to be tender with the young, compassionate with the aged, sympathetic with the striving, and tolerant with the weak and the wrong. Sometime in your life you will have been all of these.
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"Thanks for this!" says:
imark3000 (03-26-2008)