Thread: Doubts raised about drugs based on RNAi
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Old 03-26-2008, 10:51 PM
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Default Doubts raised about drugs based on RNAi
New study urges caution over revolutionary gene treatment

by Richard Ingham Wed Mar 26, 3:40 PM ET
Read entire article: http://news.yahoo.com/s/afp/20080326...c4.fFX_1is0NUE

PARIS (AFP) - A US research team on Wednesday urged strong caution over a prototype gene treatment that has generated billions of dollars in investment as a hoped-for cure for cancer, diabetes and other diseases.
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The team said they had made the surprising discovery that the therapy has a generalised effect of blocking blood-vessel growth, a phenomenon that could harm a wide range of tissues.

The method, rooted in a 1998 breakthrough that earned the Nobel Prize for Medicine in 2006, is one of several to use so-called gene silencing.
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