I take 150 mgs of Topomax for migraines and possible seizures and I still have PN (nueropathy).
I took Lyrica and had to stop because I already have balance problems and it was making me worse and I was walking into walls and the constipation issues I couldnt deal with. It didnt help the PN either.
I've been doing Anodyne therapy for the neuropathy and it has helped

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It is a physical therapy and is FDA approved. It is Monochromoatic Infrared Photo Energy or MIRE. It's designed to maximize the effectiveness of infrared photo energy to increase circulation and reduce pain in the area to which it is applied. Maybe I'll do a seperate post just for this because I have never seen anyone post on Anodyne therapy on these MS forums.
Gina Marie