So I go to my Rheumatologist appt the other day. He says the tests say negative for rheumatoid factor but that he strongly thinks that I have the kind of rheumatoid arthritis that is not detectable in the blood. Could this be or is he just trying to shut me up? He put me on Methotrexate weekly. It has been four weeks that I have been on it and I cannot tell a difference. I still have "all over pain" but mostly in joints and am still vomiting at least twice or three times weekly not to mention problems with constipation. Yeah, that's embarrassing but I have never had a problem with my bowels ever until about Feb. this year. I have to take a laxative to be able to go and if I don't, I can go about 2 whole weeks without going. Also, i still have the sores on my feet that just won't heal and periodically itch me so severely. It is baffling whatever is causing all of this not to mention affecting my activities of daily living. Does anyone have any ideas that could shed some light on my situation?