I could really identify with the second link, especially the part about the agitated anxiety. And feeling that you have too much energy within so much so that it becomes uncomfortable. That agitation is specifically what I get during what I call my major depressive episodes. I have that agitation coupled with extreme sadness, obsessive thoughts cycling over and over, and and innability to sleep. During my most recent major depression last december, I literally forced myself to go to work everyday even though I felt like crying all the time and couldn't sleep. I forced a smile onto my face and got to my cubicle as fast as I could without crying. Once settled, All I wanted to do was cry all day. But I think that because I am an accountant and my job requires so much focus, it forced me to take me mind off the obessions. The other thing I found interesting with the 2nd link is the fact that it related bipolar disorder to OCD. I found this to be very interesting because I had some of the same obsessions it discussed as being common to those with bipolar disorder. I will definately be seeking a second opinion just to be sure. I just want to find as much as I can about bipolar disorder before considering seroquel. I do agree with the concept of the disorder being part of a spectrum, with varying levels of severity.