Just another comment regarding LDN. At my last neuro appointment about two weeks ago, he asked if I thought it was working -- well I know it helps somewhat with my "bladder issues". As with the CRABS, we don't really KNOW if it's working, but he was surprised that my MS hasn't advanced more than it has having lived with this "thing" for 18 years and probably 14 before diagnosis. YEA!!!!! Of course my legs don't work much at all (thank goodness for "wheels"), but my arm strength seems to be the same as last visit and everything else is status quo.

I just wish he would have prescribed it sooner before I became SPMS. The 3.0 mg seems to work for me, the 4.5 caused my legs to become too stiff. Have trouble with spasticity anyway.

It's worth a try!!!