I won't be doing it this year as we'll be moving to Italy right about that time. I did the one that goes from Annapolis to Baltimore. Here are some things I did to raise the $1500

Sent out letters to everyone I knew requesting donations. I'm not out to most of my family because I don't want my mom to know (she has MS too) but I did mention my mom in it and why it was so important. I got a lot of donations that way. I also sent out emails linking to my fundraising page. I had a giant garage sale. My friend and I put together all of our junk and then I sent letters to all my neighbors telling them what I was doing and asked them for their junk that they wanted to get rid of. They got receipts for it and I ended up with enough stuff that we made almost $700. We priced everything dirt cheap and made money on volume.

I didn't do it, but coldstone creamery will let you use their store to raise money (you scoop and a percentage of the profits go to your cause). Selling items on Craig's List, walking dogs, donation jars at places you frequent, etc. Lots of good ways to do it. You'd be amazed at the generosity of people when there's some personal meaning in the cause. I met a neighbor with MS and one who's parent had it.

Good luck - I hope you decide to do it!