I take mine because I don't have a problem traveling with it. It can be at room temp for up to 30 days now. If I had issues - I wouldn't worry about it. I've skipped two in a week without a problem - but if you're worried, call the neuro. I bet he'll give you a bye.
Can't tell you about drug interactions and alcohol. I drink on Rebif, but have no idea if it interacts with Cymbalta. Check with your pharmacist!
Oh yea - and have a fabulous time. It's really beautiful there this time of year! (ok it's beautiful anytime of year - but especially now!)