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Source: American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) Released: Wed 27-Oct-2004, 10:00 ET
Embargo expired: Fri 05-Nov-2004, 14:00 ET Printer-friendly Version


Pain Often Overlooked in Myasthenia Gravis Patients
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MYASTHENIA GRAVIS PAIN MANAGEMENT
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Myasthenia gravis, a neuromuscular disorder primarily characterized by muscle weakness and muscle fatigue, reported in a new survey by Penn State University researchers that the disease impacts their quality of life.




Newswise — Patients with myasthenia gravis (MG), a neuromuscular disorder primarily characterized by muscle weakness and muscle fatigue, reported in a new survey by Penn State University researchers that the disease impacts their quality of life.

While this finding is not totally unexpected, the fact that a significant percentage reported experiencing pain as a result of their illness is. “That such a large number of surveyed patients reported pain associated with their disease,” explained researcher Dr. Milind Kothari, “is very surprising.”

Kothari and fellow researcher, Dr. Kevin Scott, anticipated that most of those surveyed would indicate that MG limits their ability to work or perform moderately intense activities. “We were surprised, though, to see 50% of the patients report experiencing significant pain as a result of their illness with over a quarter reporting pain of moderate or greater severity. Pain is not commonly associated with this disease.”

The surprising aspect of the survey results is that the patients’ physicians were generally not aware that their patients were in pain and, consequently, failed to treat it appropriately. The authors recommend physicians should routinely query their MG patients about pain and decide if this warrants treatment.

Myasthenia Gravis results from an abnormal immune reaction in which the body's natural immune defenses (i.e., antibodies) inappropriately attack and gradually destroy certain receptors in muscles that receive nerve impulses.

Most individuals with MG develop weakness and drooping of the eyelids; weakness of eye muscles, resulting in double vision; and excessive muscle fatigue following activity. In addition, in about 10 percent of cases, affected individuals may develop potentially life-threatening complications due to severe involvement of muscles used during breathing. Although the disorder usually becomes apparent during adulthood, symptom onset may occur at any age.

The full survey results will be reported at the 51st annual meeting of the American Association of Electrodiagnostic Medicine in Savannah, Georgia, November 3-6.

The AAEM is the largest organization worldwide (approximately 5000 members) dedicated to advancing neuromuscular, musculoskeletal, and electrodiagnostic medicine. The primary goal of the AAEM is to increase the quality of patient care, specifically for those patients with disorders of the central and peripheral nervous systems, neuromuscular junction, and skeletal muscles. This is accomplished through programs in education, research, and quality assurance. The AAEM believes that only physicians trained in electrodiagnostic procedures should perform needle electromyography and interpret nerve conduction studies to assure patients receive the proper diagnosis.



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