Sassy, it's different for everyone. Jim originally took Beta, then Copax, then Avonex. He is now back to Beta and does just fine on it. Avonex just about wiped him out every shot. He would be down for days with fevers. Copax just didn't seem to be working. On Beta he has leg cramps the next day but nothing Ibuprofen can't handle. The only draw back is remembering to take a shot every other day. His neuro refuses to put him on any of the newer drugs since his reaction to Avonex was so rough. BUT, with that being said, after taking Avonex he only had one active lesion. So, in our opinion it was working and doing it's job. We are hoping for the same outcome with Beta since he tolerates it the best.

Cindy brought up a good point. Jim has experienced depression with Beta. He's now on Zoloft and doing fine.