There are several main opinions on the genes related to the gluten syndrome.

1. Standard celiac speak states that 99% of celiac (subset) patients carry HLA DQ 2 or 8 and these genes predispose thep atient to the gluten syndrome pathways. They specifically refer to villi damage (celiac damage)

2. Ken Fine of Enterolab.com, a research lab, has announced but not published that he finds in his research that HLA 1 and 3 are related to the gluten syndrome (not necessarily the villi damaged subtype). In this region he finds almost no HLA DQ 4 (only 4) genes in patients with the gluten syndrome. All others hve been found to be involved in some of the folks he tests.

3. Dr. Aristo Vojdani or Immunosciences Laboratories believes that the genes are not necessary for some of the gluten syndrome pathways/reactions to occur. However he did not look for the 1 or 3 genes, only 2 and 8. Dr. Vojdani believes toxins (chemical injury), stress and infections can mediate the various gluten syndrome pathways without the genetic predisposition.

This is my first post. I hope I did everything right.

Hope this helps,
Olive Kaiser