Ive used and still do use Duragesic 75mcg every 2 days,I refuse generics as they dont work well. The manufactur is a subsiderary of Johnson & Johnson and for FREE will send you a box of 50 clear adhesive bandages to go over the Duragesic Patch. You must contact them and provide proof of purchase,Ive been getting them for years so I can swim and they do a great job of not allowing water in. Also,for those living in hot climates..Its a proven fact thea the med goes through your system faster when in hot weather,most doctors know this and will swith the dose from every 3 days to 2 days if you notice the drug isnt there on the third day,Good Luck!