Thread: Mucuna Pruriens
View Single Post
Old 05-04-2008, 08:33 AM
reverett123's Avatar
reverett123 reverett123 is offline
In Remembrance
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
reverett123 reverett123 is offline
In Remembrance
reverett123's Avatar
 
Join Date: Aug 2006
Posts: 3,772
15 yr Member
Default Starting to make sense

Figured a few things out-
1- The bleeding question I raised about Zandopa is inherent to mucuna itself and is, in fact, used to advantage in treating certain bites of poisonous snakes. But it seems to require a high dose. Use your bleeding when you floss as a gauge.

2- There are enzymes in mucuna that block trypsin in your small intestine. Again, high doses over a sustained period can make it a serious problem. Heat breaks the anti-trypsin agent down without affecting the Ldopa. I had had two nights of stomach cramps. Baked the mucuna at 350 degrees F for five minutes and seems to have taken care of the problem.

3- I had been trying to use mucuna integrated in with the other meds. Sinemet, in particular, to piggyback on the carbidopa protection. In particular I wanted to take advantage of the fast "on" in the mornings. Started having major problems getting anything OTHER than the mucuna to work. Worried about the possibility of some shift in receptors. But KISS as they say. Mucuna acts so fast compared to meds and it has such a high protein content that it was blocking either the uptake from the gut or the receptors in the brain or both. By taking it first thing I was, in effect, starting a daily cycle that meant that mucuna was, indeed, the only thing that worked. Started today the old, pre-mucuna way and everything works like it did including the slow start.

So, now, I tinker with schedules.

-Rick
__________________
Born in 1953, 1st symptoms and misdiagnosed as essential tremor in 1992. Dx with PD in 2000.
Currently (2011) taking 200/50 Sinemet CR 8 times a day + 10/100 Sinemet 3 times a day. Functional 90% of waking day but fragile. Failure at exercise but still trying. Constantly experimenting. Beta blocker and ACE inhibitor at present. Currently (01/2013) taking ldopa/carbadopa 200/50 CR six times a day + 10/100 form 3 times daily. Functional 90% of day. Update 04/2013: L/C 200/50 8x; Beta Blocker; ACE Inhib; Ginger; Turmeric; Creatine; Magnesium; Potassium. Doing well.
reverett123 is offline   Reply With QuoteReply With Quote
"Thanks for this!" says:
sunflower4u (05-04-2008)