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I also found that by giving a bolus of the medication (i.e., daily dose all at once) the medication was very much more effective.
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You are exactly right.
My Dr had me start out slowly with Lyrica to watch for side effects. I had none. Started out with 75mg 2x a day, went to 75mg 4x, then to 150mg alternating with 75mg 4x a day. After a while I found more relief with 225mg twice a day and have kept with it.
Lyrica has allowed me to go from 400mg a day of Tramadol plus two Vicodin down to 150mg of Tramadol and one Vicodin. Hope to slowly cut out the Tramadol entirely.